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Burkhard Luy
Prof. Dr. Burkhard Luy


Professur für Bioanalytik
Institut für Organische Chemie
Fritz-Haber-Weg 6
76131 Karlsruhe

Institut für Biologische Grenzflächen 4
Magnetische Resonanz
Postfach 3640
D-76021 Karlsruhe

Curriculum Vitae


Sekretariat / Secretary

Janine Moritz

Institut für Biologische Grenzflächen 4
Magnetische Resonanz
Postfach 3640
D-76021 Karlsruhe

Tel.: +49 721 608 29360


Joint project




Poster Award Euromar 2017

Herzlich Willkommen / Welcome


Our research is focused on Magnetic Resonance, the only technique to solve structure and dynamics of molecules at atomic resolution in solution. We are interested both in methods development and application. The highly interdisciplinary method development comprises theory and experiment, involving equally quantum mechanical simulations and optimizations based on principles of optimal control theory, cognitive design of overall rf-pulse sequences to address specific measurement tasks, the development of special sample preparation procedures, and the design of hardware extensions. Questions regarding data interpretation are addressed by computational chemical approaches, including basic spectroscopic rules and simple alignment-tensor approaches as well as sophisticated molecular dynamics approaches with magnetic resonance-derived constraints and quantum chemical calculations. We apply NMR spectroscopy to solve interesting/important questions in chemistry, biology, material science and medicine.

More detailed information can be found in Research .

We are always looking for master and PhD students. Especially students with a strong background in either chemistry, physics, or mathematics are highly encouraged to apply. See the website angebotene Positionen for details. Specific projects for master theses can be found here.


Recent Publications

M. Reller, S. Wesp, M.R.M. Koos, M.K. Reggelin, B. Luy, "Biphasic Liquid Crystal and the Simultaneous Measurement of Isotropic and Anisotropic Parameters by Spatially Resolved NMR Spectroscopy" , Chem. Eur. J. 10.1002/chem.201702126


M.R.M. Koos, H. Feyrer,B. Luy, Broadband RF-amplitude-dependent flip angle pulses with linear phase slope"  , Magn. Reson. Chem., doi: 10.1002/mrc.4593  (2017)


D. Schulze-Sünninghausen, J. Becker, M.R.M. Koos, B. Luy, "Improvements, extensions, and practical aspects of rapid ASAP-HSQC and ALSOFAST-HSQC pulse sequences for studying small molecules at natural abundance" , Journal of Magnetic Resonance 281 151–161, doi: 10.1016/j.jmr.2017.05.012 (2017)


L. Cato, A. Neeb, A. Sharp, V. Buzón, S.B. Ficarro, L. Yang, C. Muhle-Goll, N. C. Kuznik, R. Riisnaes, D. Nava Rodrigues, O. Armant, V. Gourain, G. Adelmant, E.A. Ntim, T. Westerling, D. Dolling, P. Rescigno, I. Figueiredo, F. Fauser, J. Wu, J. T. Rottenberg, L. Shatkina, C. Ester, B. Luy, H. Puchta, J. Troppmair, N. Jung, S. Bräse, U. Strähle, J.A. Marto, G.U. Nienhaus, B. Al-Lazikani, X. Salvatella, J.S. de Bono, A.C. Cato, M. Brown, Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer" , Elife. 2017 Aug 10;6. pii: e27159. doi: 10.7554/eLife.27159


X. Guo, E. Laryea, M. Wilhelm, B. Luy, H. Nirschl, G. Guthausen, "Diffusion in Polymer Solutions: Molecular Weight Distribution by PFG-NMR and Relation to SEC" Macromol. Chem. Phys. , 218, 1600440, DOI: 10.1002/macp.201600440 (2017)


J.T. Offenloch, J. Willenbacher, P. Tzvetkova, C. Heiler, H. Mutlu, C. Barner-Kowollik, "Degradable Fluorescent Single-Chain Nanoparticles Based on Metathesis PolymerC", .Chem. Comm. , 53, 775-778 (2017)


B.D. Weger, M. Weger, B. Görling, A. Schink, C. Gobet, C. Keime, G. Poschet, B. Jost, N. Krone, R. Hell, F. Gachon, B. Luy, T. Dickmeis, "Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids" , PLoS Genet. 2016 Dec 12;12(12):e1006512 (2016)