Pulse Shapes Optimized Using Optimal Control Theory
SURBOP90 and SURBOP180 (for Triple Resonance Experiments on 1.2 GHz Spectrometers)
Background: With the advancement of spectrometer field strengths, conventional triple resonance experiments need to cover larger and larger frequency bandwidths. With the latest spectrometer generation operating at 1.2 GHz 1H Larmor frequency, even selective pulses start to reach a limit: HNCACB and other protein triple resonance experiments require selective 90° and 180° pulses that cover the aliphatic carbon region, corresponding to approximately 24 kHz. Unfortunately, all commonly used selective pulse shapes cannot reach this bandwidth without violating the rf-amplitude specifications of available triple resonance probeheads.
Our recently optimized SURBOP90 and SURBOP180 pulses have a higher ratio of selective bandwidth to maximum rf-amplitude than standard pulses. These pulses perform better in simulations than standard pulses, e. g. Q3/Q5, and have already been tested on a 1.2 GHz spectrometer.
Downloads:
SURBOP90 (24 kHz BW, 15 kHz RF, +/-5% B1, 333 us)
SURBOP180 (24 kHz BW, 15 kHz RF, +/-5% B1, 333 us)
Both pulses were saved in .txt-format. Please change the file ending to .bruker in order to use them on a spectrometer.
A systematic approach for optimizing the robustness of pulse sequence elements with respect to couplings, offsets, and B1-field inhomogeneities (99)
Exploring the Limits of Broadband 90° and 180° Universal Rotation Pulses (97)
BEBOP / BIBOP amplitude-limited excitation and inversion pulses from "Exploring the limits..." (37)
Power-BEBOP / Power-BIBOP rf-power limited excitation and inversion pulses from "Exploring the limits..." (66)
Phase modulated pulses (51)
Broadband Excitation pulse (50 kHz Bandwidth for 1ms Pulse Length for. RF from 10 to 20 kHz, Bruker format, transforms Iz to Ix).
Broadband Excitation pulse, time-reversed (50 kHz Bandwidth for 1ms Pulse Length for RF from 10 to 20 kHz, Bruker format, transforms Ix to Iz).
180o Universal Rotation (50 kHz Bandwidth for 2ms Pulse Length for RF from 10 to 20 kHz, Bruker format).
Broadband excitation pulses (33)
Broadband Excitation pulse (40 kHz Bandwidth for 400us Pulse Length with max. RF 17.5 kHz, Bruker format).
Broadband Excitation pulse (40 kHz Bandwidth for 400us Pulse Length with max. RF 17.5 kHz, Varian format).
Broadband Excitation pulse (40 kHz Bandwidth for 500us Pulse Length with max. RF 17.5 kHz, Bruker format).
Broadband Excitation pulse (40 kHz Bandwidth for 500us Pulse Length with max. RF 17.5 kHz, Varian format).
Broadband Excitation pulse (40 kHz Bandwidth for 500us Pulse Length with max. RF 17.5 kHz and time digitization of 5us, Bruker format).
Broadband Excitation pulse (40 kHz Bandwidth for 500us Pulse Length with max. RF 17.5 kHz and time digitization of 5us, Varian format).
Broadband excitation pulses (26)
Broadband Excitation pulse (40 kHz Bandwidth for 2ms Pulse Length with max. RF 17.5 kHz, Bruker format).
Broadband Excitation pulse (40 kHz Bandwidth for 2ms Pulse Length with max. RF 17.5 kHz, Varian format).